A packed bus collided with a truck and burst into flames early on Saturday in Brazil, killing at least 22 people, the fire department said.

The bus carrying 45 passengers had a tire blowout and the driver lost control of the vehicle, which crashed into an oncoming truck loaded with tiles at 4 am on a major highway near the town of Teofilo Otoni, in Minas Gerais state.

Firefighters said they rescued 13 passengers from the wrecked bus. Three occupants of a car that also collided and was trapped under the truck survived the accident.

“Firefighters have recovered 22 bodies from the bus, and more victims are still to be removed,” fireman Alonso Vieira Junior said in a video released by the fire department.

He said a crane was needed to access another section of the bus where additional victims are located.